Yuan Chen, Noah R. Sundah, Nicholas R. Y. Ho, Auginia Natalia, Yu Liu, Qing Hao Miow, Yu Wang, Darius L. L. Beh, Ka Lip Chew, Douglas Chan, Paul A. Tambyah, Catherine W. M. Ong, Huilin Shao

16
Sep 22, 2021
Advanced Science
DOI :
10.1002/advs.202170116
Article
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Programmable Detection of SARS-CoV-2 In article number 2101155, Huilin Shao and co-workers report the collaborative coupling of enzyme–DNA nanostructures to establish multi-enzyme catalysis. Through programmable nanostructures and favorable equilibrium architecture, the technology achieves direct and sensitive detection of SARS-CoV-2 RNA in native patient samples, within 30 minutes at room temperature.
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