Ming Cui, Martin Oestreich

21
Sep 7, 2021
Chemistry – A European Journal
DOI :
10.1002/chem.202102993
Article
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A copper‐catalyzed conjugate silylation of various cyclobutenone derivatives with Me 2 PhSiZnCl·2LiCl or (Me 2 PhSi) 2 Zn· x LiCl ( x ≤ 4) to generate β‐silylated cyclobutanones is reported. Trapping the intermediate enolate with ClP(O)(OPh) 2 affords silylated enol phosphates that can be further engaged in Kumada cross‐coupling reactions to yield silylated cyclobutene derivatives.
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