Background : To date, limited mental health data are available from Arabic speaking countries and from different time points in the pandemic.Aim: To identify factors associated with symptoms of depression anxiety in the adult population of Qatar after the first COVID 19 wave. Method : We conducted a cross sectional online survey in Qatar between July and December 2020. Depression anxiety was defined as a cut off of 20 or higher on the PHQ ADS scale. Result : Of 1138 participants, 71.05% were female, 69.0% Arabs, and 70.0% Non Qataris. 77% were < 40 years (median age in Qatar is 32 years). In a fully adjusted model, six variables were significantly associated with PHQ ADS; Arab ethnicity (OR=1.67, p=0.026), never married (OR=2.04, p < 0.001 (versus married), prior history of psychiatric disorder (versus no history) (OR=1.76, p=0.039), increased worries due to social media use for COVID related news/updates (OR=1.72, p=0.003), those with a history of COVID 19 (OR=1.76, p=0.039), loneliness (OR=1.91, p < 0.001), and lower levels of religiosity (OR=0.96, p=0.039). These associations also pertained in the reduced model, with exception of religiosity which was only marginally statistically significant (OR=0.97, p=0.055).Conclusion : The potential risk factors identified may assist with anxiety and depression prevention and early intervention in future COVID 19 waves and similar crises.