Stéphanie Torrino, Eloise M. Grasset, Stephane Audebert, Ilyes Belhadj, Caroline Lacoux, Meagan Haynes, Sabrina Pisano, Sophie Abélanet, Frederic Brau, Stephen Y. Chan, Bernard Mari, William M. Oldham, Andrew J. Ewald, Thomas Bertero

Jun 7, 2021
Cell Metabolism
DOI :
10.1016/j.cmet.2021.05.009
Journal
Torrino et al. identify mechano activated glutamine catabolism as a necessary metabolic pathway for microtubule (MT) stabilization, connecting, for the first time, the mechanical forces and cell metabolism to MT dynamics. Matrix stiffening promotes glutamine dependent MT glutamylation and thereby stabilizes MTs. ...
Please Log In to leave a comment.