Play
Pause
Stop
Trajectory of apathy, cognition and neural correlates in the decades before symptoms in frontotemporal dementia
Maura Malpetti, Rogier A Kievit, P Simon Jones, Timothy Rittman, Kamen A Tsvetanov, John C van Swieten, Barbara Borroni, Daniela Galimberti, Raquel Sanchez‐Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Carmela Tartaglia, Rik Vandenberghe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonca, Isabel Santana, Christopher Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Giovanni B Frisoni, Roberta Ghidoni, Carolin Heller, Emily Todd, Martina Bocchetta, Rhian S Convery, Georgia Peakman, Katrina M Moore, Jonathan D Rohrer, James B Rowe
1
Jan 1, 2020
Alzheimer`s & Dementia
DOI :
10.1002/alz.041821
In frontotemporal dementia (FTD), apathy is reported to negatively impact the prognosis and survival of patients. The study of genetic FTD in its pre‐symptomatic period permits the investigation of markers in the early stages of disease progression. Therefore, in pre‐symptomatic gene carriers in the multicentre Genetic FTD Initiative (GENFI), we examined longitudinal apathy changes in association with cognitive decline over time, and baseline measures of atrophy.
Please Log In to leave a comment.