Yifu Hou

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Quantification of Postoperative Graft-Derived Cell-Free DNA to Evaluate the Risks of Impaired Allograft Function at Early Stage of Kidney Transplantation.

Hongji Yang, Liang Wei et 6 al.

Nov 8, 2022 in Transplantation proceedings
Graft-derived cell-free DNA (GcfDNA) is a promising biomarker for comprehensive monitoring of allograft injury because it overcomes the limitations of traditional approaches. The aim of this study is to investigate the association between the outliers of GcfDNA at initial time post transplantation and short-term renal graft function. A total of 230 recipients who underwent primary kidney transplan...


Microbial and metabolic features in renal transplant recipients with post-transplantation diabetes mellitus.

Jiayang He, Liang Wei et 10 al.

Mar 9, 2023 in International journal of urology
Post-transplantation diabetes mellitus (PTDM) is a common complication in renal transplant recipients (RTRs). Gut microbiome plays important roles in a variety of chronic metabolic diseases, but its association with the occurrence and development of PTDM is still unknown. The present study integrates the analysis of gut microbiome and metabolites to further identify the characteristics of PTDM. A ...


Whole Genome Profiling of Lung Microbiome in Solid Organ Transplant Recipients Reveals Virus Involved Microecology May Worsen Prognosis.

Lingai Pan, Yan Kang et 11 al.

Mar 16, 2022 in Frontiers in cellular and infection microbiology
Solid organ transplantation (SOT) is the final therapeutic option for recipients with end-stage organ failure, and its long-term success is limited by infections and chronic allograft dysfunction. Viral infection in SOT recipients is considered an important factor affecting prognosis. In this study, we retrospectively analyzed 43 cases of respiratory infections in SOT recipients using metagenomic ...


Exosomal miR-29b from cancer-associated fibroblasts inhibits the migration and invasion of hepatocellular carcinoma cells

Xingchao Liu, Ping Bie et 5 al.

Jan 1, 2020 in Translational cancer research
Department of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; Organ Transplantation Center, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, China; Organ Transplantation Translational Medicine Key...


Use of graft‐derived cell‐free DNA as a novel biomarker to predict allograft function after kidney transplantation

Wenjia Di, Liang Wei et 7 al.

Jul 6, 2021 in International Journal of Urology
Objective To investigate the association between graft‐derived cell‐free DNA and pretransplantation clinical variables, and to determine whether the former could be used as a novel biomarker to predict renal function. Method A total of 87 recipients who underwent primary kidney transplantation were recruited to the study. For each recipient, 10 mL peripheral blood was collected on days 1, 7, 14...


Survival and Complication of Liver Transplantation in Infants: A Systematic Review and Meta Analysis

Yifu Hou, Shan Zhong et 3 al.

Apr 29, 2021 in Frontiers in Pediatrics
Background : Modern surgical techniques and scientific advancements have made liver transplant (LT) in infants feasible. However, there are only a small number of studies examining the short as well as long term outcomes of LT in this vulnerable subset of children. Method : Comprehensive searches were done systematically through the PubMed, Scopus, and Google scholar databases. Studies that were ...

Serum Procalcitonin Correlates With Renal Function and Immune Components in Early-Stage Renal Transplant Recipients.

Xiangming Quan, Liang Wei et 9 al.

Feb 1, 2021 in Transplantation proceedings
In renal transplantation, monitoring procalcitonin (PCT) in the early post-transplant period can be a promising method for early tracking of infectious complications. However, the correlation between PCT and infection-related factors and immune components and renal function remains unclear. Between November 2017 and December 2018, 62 early-stage renal transplant recipients were selected, and 4 mL ...


LINC01419 mediated epigenetic silencing of ZIC1 promotes metastasis in hepatocellular carcinoma through the PI3K/Akt signaling pathway

Yifu Hou, Jun Gong et 5 al.

Mar 26, 2021 in Laboratory Investigation
Hepatocellular carcinoma (HCC) is a rapidly growing tumor characterized by a high potential for vascular invasion and metastasis. The purpose of our study is to explore the regulation mechanism of long noncoding RNA (lncRNA) LINC01419 on cell-cycle distribution and metastasis in hepatocellular carcinoma (HCC) by regulating zinc finger of the cerebellum (ZIC1) through PI3K/Akt signaling pathway. Bi...


Comprehensive analysis of prognostic value and immune infiltration of calpains in pancreatic cancer.

Chuan Lan, Yifu Hou et 6 al.

Dec 1, 2021 in Journal of gastrointestinal oncology
Calpains (CAPNs) are intracellular calcium-activated neutral cysteine proteinases involved in cancer initiation, progression, and metastasis. However, its role in pancreatic cancer (PC) is still unclear. This study aims to identify the prognostic value and immune infiltration of CAPNs for PC patients using comprehensive bioinformatics analyzes. We analyzed the transcription levels of CAPNs in diff...