Xiaomin Ou

Publications : 36
Aldex : 30
H-index : 10
Citations : 314


A nomogram involving immune‐inflammation index for predicting distant metastasis‐free survival of major salivary gland carcinoma following postoperative radiotherapy

Wenbin Yan, Chaosu Hu et 3 al.

Sep 1, 2022 in Cancer Medicine
The nomogram predicting distant metastasis free survival(DMFS) based on the clinicopathological factors and immune inflammation index for the major salivary gland carcinoma. Background Postoperative radiotherapy (PORT) is beneficial in the improvement of local regional control and overall survival (OS) for major salivary gland carcinomas (SGCs), and distant metastasis remained the main failure...

Elevated preradiotherapy serum lactate dehydrogenase predicts distant metastasis for lymphoepithelial carcinoma of major salivary gland following postoperative radiotherapy

Wenbin Yan, Chaosu Hu et 5 al.

Aug 24, 2022 in Head & Neck
Background To evaluate the predicting factors associated with distant metastasis (DM) for lymphoepithelial carcinoma of salivary gland (LECSG) following postoperative radiotherapy (PORT). Method We retrospectively collected 160 eligible patients from two cancer institutions. The DM rate was evaluated using competing risk method. Result The median follow up time was 65.6 months. Elevated pre...


Anatomic distribution of local recurrence of nasopharyngeal carcinoma in the Era of IMRT: Suggestion of modification of clinical target volume delineation.

Xiaomin Ou, Chaosu Hu et 6 al.

Jun 2, 2022 in Journal of Clinical Oncology
Journal of Clinical Oncology, Volume 40, Issue 16_suppl, Page e18060 e18060, June 2022.


Germline Mutation Landscape of DNA Damage Repair Genes in Nasopharyngeal Carcinoma

Xiaomin Ou, Chun-chun Hu et 3 al.

Jan 1, 2020 in International Journal of Radiation Oncology Biology Physics


Long-term efficacy and adverse effects of intensity-modulated radiotherapy for nasopharyngeal carcinoma

Xiaomin Ou, Hongmei Ying et 10 al.

Jan 1, 2016 in Chinese Journal of Radiation Oncology
Objective To investigate the long-term efficacy and adverse effects of intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC). Method A total of 869 patients with biopsy-proven NPC without distant metastasis who underwent the whole course of IMRT from 2009 to 2010 were enrolled. Of all the patients, 84.8% received cisplatin-based chemotherapy. The prescribed dose to the prim...


Clinical study of multidisciplinary cooperative diagnosis and treatment system in treating common somatic dysfunction symptoms of pregnant women

Feng Qin, Li Lin et 28 al.

Jan 1, 2018 in Chinese Journal of Obstetrics and Gynecology
Objective To explore the clinical effects of clinical diagnosis and treatment system of physiological regulation, psychological adjustment, music conditioning (PPM) under multidisciplinary cooperative model in treating common somatic dysfunction symptoms of pregnant women. Method A total of 93 pregnant women with 6 common somatic dysfunction symptoms including nausea, vomit, gastric distention,...


Ion and water binding sites inside an occluded hourglass pore of a TRIC channel

Xiaomin Ou, Zhenfeng Liu et 6 al.

Jan 1, 2017 in BMC Biology


Structural Insights into Substrate Selectivity, Catalytic Mechanism, and Redox Regulation of Rice Photosystem II Core Phosphatase

Xiuying Liu, Zhenfeng Liu et 4 al.

Jan 1, 2019 in Molecular Plant
Photosystem II (PSII) core phosphatase (PBCP) selectively dephosphorylates PSII core proteins including D1, D2, CP43, and PsbH. PBCP function is required for efficient degradation of the D1 protein in the repair cycle of PSII, a supramolecular machinery highly susceptible to photodamage during oxygenic photosynthesis. Here we present structural and functional studies of PBCP from Oryza sativa (OsP...

EZH2 suppresses the nucleotide excision repair in nasopharyngeal carcinoma by silencing XPA gene

Yuxiang Huang, Chaosu Hu et 11 al.

Jun 10, 2016 in Molecular Carcinogenesis


Indazoles as potential c-met inhibitors: Design, synthesis and molecular docking studies

Lianbao Ye, Shuguang Wu et 8 al.

Jul 1, 2013 in European Journal of Medicinal Chemistry
Deregulation of the receptor tyrosine kinase c-Met has been implicated in several human cancers and is considered as an attractive target for small molecule drug discovery. In this study, a series of indazoles were designed, synthesized and evaluated as novel c-Met inhibitors. The results showed that the majority of the compounds exhibited significant inhibition on c-Met and compound 4d showed hig...

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