Xiao Fu

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Provable Subspace Identification Under Post-Nonlinear Mixtures

Qi Lyu, Xiao Fu

Oct 14, 2022 in Arxiv
Unsupervised mixture learning (UML) aims at identifying linearly or nonlinearly mixed latent components in a blind manner. UML is known to be challenging: Even learning linear mixtures requires highly nontrivial analytical tools, e.g., independent component analysis or nonnegative matrix factorization. In this work, the post-nonlinear (PNL) mixture model -- where unknown element-wise nonlinear fun...

OmniObject3D: Large-Vocabulary 3D Object Dataset for Realistic Perception, Reconstruction and Generation

Tong Wu, Ziwei Liu et 11 al.

Jan 18, 2023 in Arxiv
Recent advances in modeling 3D objects mostly rely on synthetic datasets due to the lack of large-scale realscanned 3D databases. To facilitate the development of 3D perception, reconstruction, and generation in the real world, we propose OmniObject3D, a large vocabulary 3D object dataset with massive high-quality real-scanned 3D objects. OmniObject3D has several appealing properties: 1) Large Voc...

Uncovering migration systems through spatio-temporal tensor co-clustering

Zack W. Almquist et 5 al.

Dec 31, 2021 in Arxiv
A central problem in the study of human mobility is that of migration systems. Typically, migration systems are defined as a set of relatively stable movements of people between two or more locations over time. While these emergent systems are expected to vary over time, they ideally contain a stable underlying structure that could be discovered empirically. There have been some notable attempts t...

Multilevel heuristic LED regime for stimulating lipid and bioproducts biosynthesis in Haematococcus pluvialis under mixotrophic conditions.

Na Pang, Shulin Chen et 3 al.

May 23, 2019 in Bioresource technology
Enhanced biosynthesis and overproduction of lipid and high-value bioproducts endows microalgae as a promising feedstock for the cost-effective development of advanced bioenergy currently. In this study, multilevel heuristic LED regimes, designed with the coordination of light, nitrogen and carbons in terms of cell physiology and morphology, have been implemented to significantly induce the growth ...


Interplay of adherens junctions and matrix proteolysis determines the invasive pattern and growth of squamous cell carcinoma.

Takuya Kato, Erik Sahai et 11 al.

Mar 9, 2023 in eLife
Cancers, such as squamous cell carcinoma, frequently invade as multicellular units. However, these invading units can be organised in a variety of ways, ranging from thin discontinuous strands to thick 'pushing' collectives. Here we employ an integrated experimental and computational approach to identify the factors that determine the mode of collective cancer cell invasion. We find that matrix pr...

Long-term chemical fertilization results in a loss of temporal dynamics of diazotrophic communities in the wheat rhizosphere.

Xiao Fu, Haiyan Chu et 7 al.

Mar 7, 2023 in The Science of the total environment
Diazotrophs are potential bacterial biofertilizers with efficacy for plant nutrition, which convert atmospheric N2 into plant available nitrogen. Although they are known to respond strongly to fertilization, little is known about the temporal dynamics of diazotrophic communities throughout plant developmental under different fertilization regimes. In this study, we investigated diazotrophic commun...

Hydrogen sulfide in health and diseases: crosstalk with noncoding RNAs.

Qing-Bo Lu, Ji-Ru Zhang et 4 al.

Mar 6, 2023 in American journal of physiology. Cell physiology
Hydrogen sulfide (H2S) is previously described as a potentially lethal toxic gas. However, this gasotransmitter is also endogenously generated by the actions of cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST) in mammalian systems, thus belonging to the family of gasotransmitters after nitric oxide (NO) and carbon monoxide (CO). The physi...


PD‐L1 regulates epithelial–mesenchymal transition and cancer stem cell phenotypes in Hepatocellular Carcinoma through SGK2/β‐catenin signaling pathway

Xin Kong, Dazhi Zhang et 5 al.

Feb 8, 2023 in Cancer Science
PD‐L1 plays an important role in the occurrence of Hepatocellular Carcinoma (HCC). Present study indicated that epithelial–mesenchymal transition (EMT) and induction of cancer stem cell (CSC)‐like properties contribute to metastasis of cancers. However, the molecular mechanisms underlying PD‐L1 and EMT and CSC phenotypes in HCC remain to be elucidated. Here, we report that PD‐L1 regulates not onl...