Xiangmei Kong

Publications : 69
Aldex : 60
H-index : 14
Citations : 746


Effect of selective laser trabeculoplasty on intraocular pressure in patients with glucocorticoid induced glaucoma

Junyi Chen, Xinghuai Sun et 2 al.

Jan 1, 2014 in Chinese Journal of Experimental Ophthalmology
Background Glucocorticoid drugs have been used increasingly in ophthalmology. It has been established that glucocorticoid are associated with a rise in intraocular pressure (IOP) and the development of glaucoma. Selective laser trabeculoplasty (SLT) is thought to be effective in treating patients with glucocorticoidinduced elevated IOP. Objective This study was to assess the efficacy of SLT in l...

Contribution of gut microbiota toward renal function in sepsis.

Yaya Xu, Xiaodong Zhu et 7 al.

Sep 6, 2022 in Frontiers in microbiology
Sepsis most often involves the kidney and is one of the most common causes of acute kidney injury. The prevalence of septic acute kidney injury has increased significantly in recent years. The gut microbiota plays an important role in sepsis. It interacts with the kidney in a complex and multifactorial process, which is not fully understood. Sepsis may lead to gut microbiota alteration, orchestrat...


LZK dependent stimulation of astrocyte reactivity promotes corticospinal axon sprouting

Meifan Chen et 9 al.

Sep 15, 2022 in Frontiers in Cellular Neuroscience
Injury to the adult mammalian central nervous system induces compensatory plasticity of spared axons—referred to as collateral axon sprouting—that can facilitate neural recovery. The contribution of reactive astrocytes to axon sprouting remains elusive. Here, we sought to investigate the role of axon degeneration reactive astrocytes in the regulation of collateral axon sprouting that occurs in the...


The characteristics of fundus microvascular alterations in the course of glaucoma: a narrative review.

Xintong Fan, Xiangmei Kong et 6 al.

May 1, 2022 in Annals of translational medicine
As the vascular theory has led many researchers to focus on vascular dysfunction in the pathogenesis of glaucoma, a better understanding of ocular microcirculation would be of great significance. The emergence of optical coherence tomography angiography (OCTA) has shed light on the various fundus microvascular changes that occur in glaucoma, thus providing ample evidence in the role of microvascul...


Outcomes of combined phacoemulsification, anterior vitrectomy, and sclerectomy in nanophthalmic eyes with glaucoma

Xintong Fan, Xiangmei Kong et 4 al.

Apr 5, 2022 in Eye
Objective To compare the long-term efficacy and safety of combined phacoemulsification, anterior vitrectomy, and sclerectomy (triple procedure surgery, TS); combined phacoemulsification and anterior vitrectomy (double procedure surgery, DS); and filtering surgery (FS) in nanophthalmos with angle-closure glaucoma (NACG). Method Retrospective cohort study. Forty patients (44 eyes) diagnosed with NAC...

Peripapillary Vascular Reactivity in Primary Open-Angle Glaucoma With High Myopia by Using Optical Coherence Tomography Angiography.

Xintong Fan, Xiangmei Kong et 6 al.

Mar 18, 2022 in Frontiers in medicine
To evaluate peripapillary vascular reactivity in primary open-angle glaucoma (POAG) with and without high myopia (HM) by using optical coherence tomography angiography (OCTA). This prospective study enrolled 48 eyes with POAG, including 16 and 32 eyes with and without HM, respectively. The retinal peripapillary vessel density (VD) was repeatedly assessed using OCTA at baseline and after a hyperoxi...


Outcomes of noninvasive neurally adjusted ventilatory assist and nasal continuous positive airway pressure in preterm infants: a systematic review and meta-analysis.

Yaya Xu, Jiru Li et 3 al.

Jan 18, 2022 in Archivos argentinos de pediatria
The benefits of neurally adjusted ventilatory assist (NAVA) in preterm infants are unclear. This study aimed to explore if noninvasive NAVA is more beneficial for preterm infants than nasal continuous positive airway pressure (NCPAP). Meta-analysis was performed in three clinical trials comprising two randomized controlled trials and one crossover study. We compared NIV-NAVA and NCPAP and reported...


2% Ganciclovir Eye Drops Control Posner Schlossman Syndrome Relapses With/Without Cytomegalovirus Intraocular Reactivation

Qilian Sheng, Xiangmei Kong et 3 al.

Mar 9, 2022 in Frontiers in Medicine
Background To observe and compare the efficacy of 2% ganciclovir eye drops in the treatment of Posner Schlossman Syndrome relapses with/without cytomegalovirus intraocular reactivation. Method A prospective cohort study enrolling 101 patients diagnosed unilateral Posner Schlossman Syndrome in Eye & ENT hospital, Fudan University, Shanghai, China. Thorough ophthalmic examinations were given. Aqueo...


Prolonged release of VEGF and Ang1 from intralesionally implanted hydrogel promotes perilesional vascularization and functional recovery after experimental ischemic stroke.

Pavel Yanev et 6 al.

Jan 5, 2022 in Journal of cerebral blood flow and metabolism
Injectable hydrogels can generate and support pro-repair environments in injured tissue. Here we used a slow-releasing drug carrying in situ-forming hydrogel to promote post-stroke recovery in a rat model. Release kinetics were measured in vitro and in vivo with MRI, using gadolinium-labeled albumin (Galbumin), which demonstrated prolonged release over multiple weeks. Subsequently, this hydrogel w...


Retinal Microcirculatory Responses to Hyperoxia in Primary Open-Angle Glaucoma Using Optical Coherence Tomography Angiography.

Xintong Fan, Xiangmei Kong et 4 al.

Nov 1, 2021 in Investigative ophthalmology & visual science
To investigate the retinal vascular response to hyperoxia in patients with primary open-angle glaucoma (POAG) using optical coherence tomography angiography (OCTA). This prospective study included 27 eyes in 27 patients with POAG and 14 eyes in 14 age- and sex-matched healthy participants. Retinal radial peripapillary capillary (RPC) perfusion was measured by OCTA before and after inhaling oxygen ...

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