Won-Suk Chung

Publications : 43
Aldex : 50
H-index : 18
Citations : 4506


science

Author Correction: Stroke subtype-dependent synapse elimination by reactive gliosis in mice.

Xiaojing Shi, Guo-Yuan Yang et 14 al.

Feb 28, 2022 in Nature communications

science

Stroke subtype dependent synapse elimination by reactive gliosis in mice

Xiaojing Shi, Guo-Yuan Yang et 14 al.

Nov 26, 2021 in Nature Communications
The pathological role of reactive gliosis in CNS repair remains controversial. In this study, using murine ischemic and hemorrhagic stroke models, we demonstrated that microglia/macrophages and astrocytes are differentially involved in engulfing synapses in the reactive gliosis region. By specifically deleting MEGF10 and MERTK phagocytic receptors, we determined that inhibiting phagocytosis of mic...

chemistry

CDC50A dependent phosphatidylserine exposure induces inhibitory post-synapse elimination by microglia

Jungjoo Park, Won-Suk Chung et 3 al.

Jan 1, 2020 in bioRxiv
Glia contribute to synapse elimination through phagocytosis in the central nervous system. Despite important roles during development and neurological disorders, the “eat-me” signal that initiates glia-mediated phagocytosis of synapses remains largely elusive. Here, by generating inducible conditional knockout mice of Cdc50a, we induced stable exposure of phosphatidylserine in the neuronal outer m...

Early-stage evaluation of emerging CO2 utilization technologies at low technology readiness levels

Kosan Roh et 16 al.

Jan 1, 2020 in Green Chemistry
Most CO2 utilization technologies are at low technology readiness levels (TRLs). Given the large number of potential technologies, screening to identify the most promising ones should be conducted before allocating large RD co-electrolysis of CO2 and water for ethylene production (TRL 2–4); direct oxidation of CO2-based methanol for oxymethylene dimethyl ether (OME1) production (TRL 4); and microa...

medicine

The roles of astrocytic phagocytosis in maintaining homeostasis of brains.

Se Young Lee, Won-Suk Chung

Jan 1, 2021 in Journal of pharmacological sciences
In the central nervous system, microglia are regarded as the main cells responsible for phagocytosis, contributing to neural circuit refinement and homeostasis through synapse elimination. However, recent findings have shown that astrocytes also actively participate in synapse homeostasis through phagocytosing synapses, neuronal debris, axonal mitochondria, and pathological protein aggregates. In ...

biology

Regulation of adult hippocampal synaptic transmission by astrocytic synapse pruning

Ji Young Kim, Hyungju Park et 4 al.

Jan 1, 2019 in IBRO Reports


Performance Optimization of Polymer Solar Cells Using Electrostatically Sprayed Photoactive Layers

Joon-Sung Kim et 7 al.

Aug 4, 2010 in Advanced Functional Materials
Polymer solar cells (PSCs) are fabricated using a novel fi lm deposition method, the electrostatic spray (e-spray) technique. Stable atomization and uniform deposition of the polymer blend by e-spray are achieved by manipulating the solution concentration, the solvent composition, and the electric fi eld. The performance of PSCs is primarily infl uenced by the inherent fi lm morphology of the e-sp...

The role of glial cells in synapse elimination

Won-Suk Chung, Ben A Barres

Jun 1, 2012 in Current Opinion in Neurobiology

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