zur kostengünstigen und effizienten In situ-Sanierung von organischen Bodenund Grundwasserkontaminationen eingesetzt. Dabei werden starke Oxidationsmittel in den Untergrund infiltriert. Dort erfolgt in-situ die Oxidation der Schadstoffe, die abhängig von der Struktur der Verbindungen bis zu deren Komplettabbau führen kann. Für ISCO-Verfahren werden häufig folgende Oxidationsmittel verwendet: Perma...
Multispectral photoacoustic imaging enables the measurement of the optical absorption of various tissue components or exogenous contrast agents in vivo. The dominant, near infrared absorbing chromophores in human tissue are oxy- and deoxyhemoglobin followed by collagen, melanin and lipids. The multispectral measurement of the absorption of hemoglobin shows changes in blood oxygen saturation and bl...
To demonstrate dosimetry benefits and report clinical outcomes of stereotactic magnetic resonance (MR)-guided online adaptive radiotherapy (SMART) of abdominopelvic lymphatic oligometastases. Prospective registry data of 26 patients with 31 oligoprogressive lymphatic metastases (1-2 lesions) who received SMART between April 2020 and April 2021 was analyzed. Prostate cancer was the most common hist...
Proton beam radiotherapy (PRT) is used in the treatment of low-grade glioma (LGG) to mitigate long-term sequelae. Following PRT, increased rates of radiation-induced contrast enhancements (RICE) are suspected but poorly understood. We analyzed consecutive 227 patients (42 children and 185 adults) treated with PRT (54Gy RBE) for LGG from 2010 to 2020 and followed with serial clinical exams and magn...
The Swiss press occasionally describes the construction of the KKL as a “miracle.” Why? Decisive in this respect was certainly not solely the fact that the project garnered tremendous acclaim in Switzerland, but rather above all the facility’s very high level of acceptance among, first and foremost, conductors — such as Claudio Abbado — artists and musicians. The international press as well was, t...
Besides its well-established effects on granulocytopoiesis, granulocyte colony-stimulating factor (G-CSF) has been shown to have direct effects on the recruitment and bactericidal ability of neutrophils, resulting in improved survival of experimentally infected animals. The effect of G-CSF on the course of experimental pneumonia induced by Klebsiella pneumoniae was studied. Using a highly reproduc...
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Acinic cell carcinoma is a rare disease treated usually by surgery. The role of radiotherapy is controversially discussed. In this retrospective analysis based on 15 patients undergoing postoperative or definitive radiotherapy (intensity-modulated radiotherapy, IMRT) with carbon ion radiotherapy boost leads to excellent results after R1-resection, and is a promising treatment modality in ...