Siwoo Lee

Publications : 71
Aldex : 10
H-index : 11
Citations : 506

Cascade regulation of PPARγ2 and C/EBPα signaling pathways by celastrol impairs adipocyte differentiation and stimulates lipolysis in 3T3-L1 adipocytes

Seung Kug Choi et 8 al.

May 1, 2016 in Metabolism
OBJECTIVE Celastrol, a triterpene from the root bark of the Chinese medicinal plant Tripterygium wilfordii, has been shown to exhibit anti-oxidant, anti-inflammatory, anti-cancer and insecticidal activities. Also, it has been demonstrated that celastrol has obesity-controlling effects in diet-induced obesity mice. However, direct evidence that celastrol contributes to the development of adipocyte ...

Prediction of metabolic and pre-metabolic syndromes using machine learning models with anthropometric, lifestyle, and biochemical factors from a middle-aged population in Korea.

Junho Kim, Younghwa Baek et 4 al.

Apr 6, 2022 in BMC public health
Metabolic syndrome (MetS) is a complex condition that appears as a cluster of metabolic abnormalities, and is closely associated with the prevalence of various diseases. Early prediction of the risk of MetS in the middle-aged population provides greater benefits for cardiovascular disease-related health outcomes. This study aimed to apply the latest machine learning techniques to find the optimal ...


Machine learning-based prediction of Sasang constitution types using comprehensive clinical information and identification of key features for diagnosis

Sa-Yoon Park, Chang-Eop Kim et 6 al.

Jan 1, 2021 in Integrative Medicine Research
Background Despite the importance of accurate Sasang type diagnosis, a unique form of Korean medicine, there have been concerns about consistency among diagnoses. We investigate a data-driven integrative diagnostic model by applying machine learning to a multicenter clinical dataset with comprehensive features. Method Extremely randomized trees (ERT), support vector machines, multinomial logist...


Metabolic Syndrome Prediction Models Using Machine Learning and Sasang Constitution Type

Ji-Eun Park, Siwoo Lee et 2 al.

Jan 1, 2021 in Evidence-based Complementary and Alternative Medicine : eCAM
Background Machine learning may be a useful tool for predicting metabolic syndrome (MetS), and previous studies also suggest that the risk of MetS differs according to Sasang constitution type. The present study investigated the development of MetS prediction models utilizing machine learning methods and whether the incorporation of Sasang constitution type could improve the performance of those ...


Effect of Lifestyle Factors on Hypertension by Constitution Type: A Large Community-Based Study

Ji-Eun Park, Siwoo Lee et 2 al.

Jan 1, 2019 in Evidence-based Complementary and Alternative Medicine
Background . The risk of hypertension differs according to lifestyle factors and individual constitution types. The aim of this study was to investigate the effect of lifestyle factors on hypertension and to assess whether those effects differ according to the constitution types. Method . A total of 5,793 men and women were recruited between 2012 and 2014. Odds ratios for hypertension associated ...

Compact tomographic near eye display using a MEMS scanning mirror

Minkwan Kim, Byoungho Lee et 4 al.

Sep 1, 2021 in Optics Letters
We propose a compact tomographic near eye display by combining a micro–electro–mechanical systems (MEMS) scanning mirror ...

Similar author:

Xianshu Luo