Shinya Abe

Publications : 124
Aldex : 80
H-index : 16
Citations : 865


Correlation between Severity of Fetal Growth Restriction and Oxidative Stress in Severe Small-for-Gestational-Age Infants.

Mariko Ashina et 10 al.

Oct 13, 2021 in International journal of environmental research and public health
Severe small-for-gestational-age (sSGA) infants exhibit increased mortality and morbidity. Oxidative stress is suggested to be involved in intrauterine growth restriction. This retrospective study aimed to evaluate the oxidative stress level at birth in an sSGA population. Sera of 28 sSGA (sSGA group) and 31 non-sSGA (control group) infants, born at our hospital between March 2017 and March 2020, ...

Clinical features and visual outcomes of ocular sarcoidosis at a tertiary referral center in Tokyo.

Katsuya Nagahori et 8 al.

May 26, 2022 in Graefe's archive for clinical and experimental ophthalmology
To analyze clinical features, treatment, complications, and visual outcomes of ocular sarcoidosis at a tertiary center in Tokyo. Clinical records of 53 patients with ocular sarcoidosis ("definite" or "presumed") presenting between 2013 and 2018 to the Kyorin Eye Center were retrospectively reviewed. Diagnosis was based on the revised criteria of the International Workshop on Ocular Sarcoidosis. De...

Changes in Lysophospholipid Components in Ulcerative Colitis and Colitis-associated Cancer.

Hirofumi Sonoda et 16 al.

May 1, 2022 in Anticancer research
In recent years, it has become clear that, in addition to normal cytokines, phospholipid mediators play an important role in the development, growth, infiltration, and metastasis of cancer and in the cancer microenvironment. A phospholipid analysis method using tandem mass spectrometry (LC-MS/MS) with high detection sensitivity has enabled quantification of phospholipids, even when using a very sm...

CD133( plus )HIF-1α(-) Expression After Chemoradiotherapy Predicts Poor Prognosis in Rectal Cancer.

Yuichi Tachikawa et 14 al.

Apr 1, 2022 in Anticancer research
CD133 and hypoxia-inducible factor 1α (HIF-1α) have been reported to be affected by chemoradiotherapy (CRT), but the combinatorial assessment of these markers for prognosis after CRT has not been fully investigated. Therefore, we aimed to predict recurrence and prognosis in patients with rectal cancer by assessing changes in the expression of both CD133 and HIF-1α after CRT. CD133 and HIF-1α expre...

Artificial Intelligence Program to Predict p53 Mutations in Ulcerative Colitis-Associated Cancer or Dysplasia.

Tatsuki Noguchi et 17 al.

Mar 12, 2022 in Inflammatory bowel diseases
The diagnosis of colitis-associated cancer or dysplasia is important in the treatment of ulcerative colitis. Immunohistochemistry of p53 along with hematoxylin and eosin (H&E) staining is conventionally used to accurately diagnose the pathological conditions. However, evaluation of p53 immunohistochemistry in all biopsied specimens is expensive and time-consuming for pathologists. In this study, w...

chemistry

Synthesis of (S)-N-(endo -8-methyl-8-azabicyclo[3.2.1] oct-3α-yl)-4-amino-5-chloro-2-(1-methyl-2-butynyloxy) [carbonyl-14C]benzamide monohydrochloride (14C-E3620)

Yorihisa Hoshino, Shinya Abe et 5 al.

Jan 1, 1997 in Journal of Labelled Compounds and Radiopharmaceuticals
(S)-N-(endo-8-Methyl-8-azabicyclo[3.2.1]oct-3α-yl)-4-amino-5-chloro-2-(1-methyl-2-butynyloxy)[carbonyl-14C]benzamide monohydrochloride (14C-E3620, 1 1), which was required for a study of the pharmacokinetic profile of E3620, is not only a potent antagonist of 5-HT3 receptors but also a potent agonist of 5-HT4 receptors. It was synthesized using (S)-5-chloro-4-(2,5-dimethylpyrrol-1-yl)-2-(1-methyl-...

medicine

A 29-YEAR-OLID CASE OF PRIMARY ADENOCARCINOMA OF THE ESOPHAGUS

Tohru Kikuchi et 14 al.

Jan 1, 1995 in Acta Gastro-enterologica Belgica

medicine

DUPLICATION OF INTESTINE PRESENTED WITH AN INTRA-ABDOMINAL ABSCESS-A CASE REPORT-

Takao Mizumoto et 6 al.

Jan 1, 2009 in Nihon Rinsho Geka Gakkai Zasshi
消化管重複症は非常に稀な消化管奇形であり消化管のいずれの部位にも発生するが,炎症所見を伴うものは報告では8.6%と少ない.今回われわれは腹腔内膿瘍を契機に発見された消化管重複症の1例を経験したので報告する.症例は69歳,男性.間歇的な腹痛を主訴に当院を受診した.腹部USとCTにて石灰化を伴う小腸壁肥厚を認め,魚骨を誤飲した可能性があることから,消化管異物による腹腔内膿瘍の診断で入院となった.抗生剤などによる保存的加療を行うも炎症所見の増悪を認めたため開腹手術を行った.腹腔内には約5cmの腫瘤を認め,腸間膜内に腸管壁様の構造物を認めた.重複腸管症と判断し,重複腸管とともに小腸部分切除を行った.摘出標本には腸管様構造物が小腸に沿って存在し,病理所見から管状重複腸管と診断された.本例は炎症を伴って発症した消化管重複症であり,異所性胃粘膜,異所性膵組織を伴い,その報告は本例を含めて6例と極めて稀な...

Retail Trade in Deregulation

Shinya Abe, 義忠 加藤

Jan 1, 1995 in The Journal of Japan Society for Distributive Sciences

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