Shinya Abe

Publications : 124
Aldex : 80
H-index : 16
Citations : 843


IJERPH, Vol. 19, Pages 13090: Influence of UGT1A1 Genetic Variants on Free Bilirubin Levels in Japanese Newborns: A Preliminary Study

Hiroaki Hanafusa et 10 al.

Oct 12, 2022 in International Journal of Environmental Research and Public Health
IJERPH, Vol. 19, Pages 13090: Influence of UGT1A1 Genetic Variants on Free Bilirubin Levels in Japanese Newborns: A Preliminary Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph192013090 Authors: Hiroaki Hanafusa Shinya Abe Shohei Ohyama Yuki Kyono Takumi Kido Ruka Nakasone Mariko Ashina Kenji Tanimura Kandai Nozu Kazumichi Fujioka Background : Free bilir...



Control of Immunity and Allergy by Steroid Hormones.

Koichi Ikuta et 4 al.

Aug 13, 2022 in Allergology international
Steroid hormones, especially glucocorticoids, androgens, and estrogens, have profound influence on immunity. Recent studies using cell-type specific steroid hormone receptor-deficient mice have revealed the precise roles of some of these hormones in the immune system. Glucocorticoids are known to have strong anti-inflammatory and immunosuppressive effects and pleiotropic effects on innate and adap...

immunology

Androgens Alleviate Allergic Airway Inflammation by Suppressing Cytokine Production in Th2 Cells.

Aki Ejima, Koichi Ikuta et 11 al.

Aug 17, 2022 in Journal of immunology
Asthma is more common in females than males after adolescence. However, the mechanism of the sex bias in the prevalence of asthma remains unknown. To test whether sex steroid hormones have some roles in T cells during development of asthma, we analyzed airway inflammation in T cell-specific androgen receptor (AR)- and estrogen receptor (ER)-deficient mice. T cell-specific AR-deficient male mice de...

Correlation between Severity of Fetal Growth Restriction and Oxidative Stress in Severe Small-for-Gestational-Age Infants.

Mariko Ashina et 10 al.

Oct 13, 2021 in International journal of environmental research and public health
Severe small-for-gestational-age (sSGA) infants exhibit increased mortality and morbidity. Oxidative stress is suggested to be involved in intrauterine growth restriction. This retrospective study aimed to evaluate the oxidative stress level at birth in an sSGA population. Sera of 28 sSGA (sSGA group) and 31 non-sSGA (control group) infants, born at our hospital between March 2017 and March 2020, ...

Clinical features and visual outcomes of ocular sarcoidosis at a tertiary referral center in Tokyo.

Katsuya Nagahori et 8 al.

May 26, 2022 in Graefe's archive for clinical and experimental ophthalmology
To analyze clinical features, treatment, complications, and visual outcomes of ocular sarcoidosis at a tertiary center in Tokyo. Clinical records of 53 patients with ocular sarcoidosis ("definite" or "presumed") presenting between 2013 and 2018 to the Kyorin Eye Center were retrospectively reviewed. Diagnosis was based on the revised criteria of the International Workshop on Ocular Sarcoidosis. De...

Changes in Lysophospholipid Components in Ulcerative Colitis and Colitis-associated Cancer.

Hirofumi Sonoda et 16 al.

May 1, 2022 in Anticancer research
In recent years, it has become clear that, in addition to normal cytokines, phospholipid mediators play an important role in the development, growth, infiltration, and metastasis of cancer and in the cancer microenvironment. A phospholipid analysis method using tandem mass spectrometry (LC-MS/MS) with high detection sensitivity has enabled quantification of phospholipids, even when using a very sm...

CD133( plus )HIF-1α(-) Expression After Chemoradiotherapy Predicts Poor Prognosis in Rectal Cancer.

Yuichi Tachikawa et 14 al.

Apr 1, 2022 in Anticancer research
CD133 and hypoxia-inducible factor 1α (HIF-1α) have been reported to be affected by chemoradiotherapy (CRT), but the combinatorial assessment of these markers for prognosis after CRT has not been fully investigated. Therefore, we aimed to predict recurrence and prognosis in patients with rectal cancer by assessing changes in the expression of both CD133 and HIF-1α after CRT. CD133 and HIF-1α expre...

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