Ricardo A. Machado-de-Ávila

Publications : 23
Aldex : 10
H-index : 10
Citations : 227

Vaccines, Vol. 10, Pages 1146: A Recombinant Chimeric Protein Based Vaccine Containing T Cell Epitopes from Amastigote Proteins and Combined with Distinct Adjuvants, Induces Immunogenicity and Protection against Leishmania infantum Infection

Daniela P. Lage et 21 al.

Jul 19, 2022 in Vaccines
(This summary has been generated by AI. Generate your own summaries: https://www.welcome.alviss.ai/alboard/#/editorial) A recombinant chimeric protein based vaccine containing t cell epitopes from amastigote proteins and combined with distinct adjuvants, induces immunogenicity and protection against leishmania infantum infection vaccines. Chimt was associated with the adjuvant Saponin or monophosp...

medicine

In vitro synergic activity of diethyldithiocarbamate and 4-nitrochalcone loaded in beeswax nanoparticles against melanoma (B16F10) cells.

Arthur Poester Cordeiro, Claudia Sayer et 8 al.

Jan 1, 2021 in Materials science & engineering. C, Materials for biological applications
The use of nanoparticles as drug delivery systems to simultaneously carry several therapeutic agents is an attractive idea to create new synergic treatments and to develop the next generation of cancer therapies. Therefore, the goal of this study was the simultaneous encapsulation of a hydrophilic drug, sodium diethyldithiocarbamate (DETC), and a hydrophobic drug, 4-nitrochalcone (4NC), in beeswax...

chemistry

In vitro phototoxicity of zinc phthalocyanine (ZnPc) loaded in liposomes against human breast cancer cells

Paulo Emilio Feuser et 7 al.

Jan 1, 2020 in Journal of Porphyrins and Phthalocyanines

Application of ozone on rice storage: A mathematical modeling of the ozone spread, effects in the decontamination of filamentous fungi and quality attributes

Geovana D. Savi et 10 al.

Jan 1, 2020 in Journal of Stored Products Research
Rice is a food crop prone to contamination by toxigenic fungi. Ozone, as a decontamination strategy in the industry, has attractive advantages over traditional food preservation techniques. A contribution to the understanding of ozone as an antifungal agent in rice storage processes is performed in this study. For this, a mathematical model to predict the ozone spread in rice storage in silos was...

chemistry

Superparamagnetic biobased poly(thioether‐ester) via thiol‐ene polymerization in miniemulsion for hyperthermia

Paula Christina Mattos dos Santos et 8 al.

Jan 1, 2021 in Journal of Applied Polymer Science


An in silico functional annotation and screening of potential drug targets derived from Leishmania spp. hypothetical proteins identified by immunoproteomics

Miguel A. Chávez-Fumagalli et 5 al.

May 1, 2017 in Experimental Parasitology
Leishmaniasis is a parasitic disease caused by the protozoan of the Leishmania genus. While no human vaccine is available, drugs such as pentavalent antimonials, pentamidine and amphotericin B are used for treat the patients. However, the high toxicity of these pharmaceutics, the emergence of parasite resistance and/or their high cost have showed to the urgent need of identify new targets to be em...

Identification of a linear B-cell epitope in the catalytic domain of bothropasin, a metalloproteinase from Bothrops jararaca snake venom

Denis A. Molina Molina et 8 al.

Dec 1, 2018 in Molecular Immunology
&NA; Bothropasin is a hemorrhagic snake venom metalloproteinase (SVMP) from Bothrops jararaca venom, the snake responsible for most bites in Southeastern Brazil. SVMPs, such as bothropasin, are involved in the main bothropic envenoming symptoms, which include hemorrhage, inflammation, necrosis and blood coagulation deficiency. B‐cell epitope mapping of SVMPs can lead to the identification of pepti...


immunology

Evaluation of a Leishmania hypothetical protein administered as DNA vaccine or recombinant protein against Leishmania infantum infection and its immunogenicity in humans

Patrícia A.F. Ribeiro et 17 al.

May 1, 2018 in Cellular Immunology
Visceral leishmaniasis (VL) is a fatal disease when acute and untreated. The treatment against this disease is long and presents toxicity and/or high costs. Moreover, parasite resistance has been increasing. Therefore, alternative control measures to avoid the spread of disease should be considered. It is accepted that the development of the T helper (Th)1 immune response, based on the production ...

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