Monika Adamowicz

Publications : 6
Aldex : 20
H-index : 2
Citations : 19

science

Role of miR-506 in ulcerative colitis associated with primary sclerosing cholangitis.

Agnieszka Kempinska-Podhorodecka et 7 al.

May 12, 2021 in Scientific reports
Primary sclerosing cholangitis (PSC) is commonly accompanied by ulcerative colitis (UC). MicroRNA-506 modulates expression of genes which are essential for sphingosine-mediated signaling pathway and intestinal mucosa protection. We investigated whether miR-506 and its target genes are involved in phenotypic presentations of colonic inflammation and/or neoplasia. We analyzed serum and colon tissue ...

Association of Aneurysm Tissue Neutrophil Mediator Levels with Intraluminal Thrombus Thickness in Patients with Abdominal Aortic Aneurysm.

Aldona Siennicka et 8 al.

Feb 4, 2022 in Biomolecules
An intraluminal thrombus (ILT), which accumulates large numbers of neutrophils, plays a key role in abdominal aortic aneurysm (AAA) pathogenesis. This study aimed to compare levels of selected neutrophil inflammatory mediators in thick and thin ILT, plus adjacent AAA walls, to determine whether levels depend on ILT thickness. Neutrophil mediator levels were analysed by enzyme-linked immunosorbent ...

IJMS, Vol. 23, Pages 4905: Modulation of Mismatch Repair and the SOCS1/p53 Axis by microRNA 155 in the Colon of Patients with Primary Sclerosing Cholangitis

Monika Adamowicz et 6 al.

Apr 28, 2022 in International Journal of Molecular Sciences
Deficient mismatch repair (MMR) proteins may lead to DNA damage and microsatellite instability. Primary sclerosing cholangitis (PSC) is a risk factor for colitis associated colon cancer. MiR 155 is suggested to act as a key regulating node, linking inflammation and tumorigenesis. However, its involvement in the chronic colitis of PSC UC patients has not been examined. We investigated the involveme...

Biomolecules, Vol. 12, Pages 254: Association of Aneurysm Tissue Neutrophil Mediator Levels with Intraluminal Thrombus Thickness in Patients with Abdominal Aortic Aneurysm

Aldona Siennicka et 8 al.

Feb 4, 2022 in Biomolecules
An intraluminal thrombus (ILT), which accumulates large numbers of neutrophils, plays a key role in abdominal aortic aneurysm (AAA) pathogenesis. This study aimed to compare levels of selected neutrophil inflammatory mediators in thick and thin ILT, plus adjacent AAA walls, to determine whether levels depend on ILT thickness. Neutrophil mediator levels were analysed by enzyme linked immunosorbent ...

biology

Cells, Vol. 11, Pages 2880: Suppression of Hepatic PPAR&alpha in Primary Biliary Cholangitis Is Modulated by miR 155

Monika Adamowicz et 6 al.

Sep 15, 2022 in Cells
Cells, Vol. 11, Pages 2880: Suppression of Hepatic PPARα in Primary Biliary Cholangitis Is Modulated by miR 155 Cells doi: 10.3390/cells11182880 Authors: Monika Adamowicz Agnieszka Kempinska Podhorodecka Joanna Abramczyk Jesus M. Banales Piotr Milkiewicz Malgorzata Milkiewicz Background : PPARα is a ligand activated transcription factor that shows protective effects against metabolic disorders, i...

nutrition

Vitamin-D Receptor-Gene Polymorphisms Affect Quality of Life in Patients with Autoimmune Liver Diseases.

Agnieszka Kempinska-Podhorodecka et 6 al.

Jul 27, 2020 in Nutrients
Vitamin D deficiency has been associated with depressive symptoms and reduced physical functioning. The aim of the study was to characterize the relationship between polymorphisms of the vitamin D receptor (VDR) gene and the quality of life in patients with autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC). Three polymorphisms of the VDR gene (TaqI-rs731236, BsmI-rs1544410, and ApaI...

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