Minhu Chen

Publications : 0
Aldex : 0
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Citations : 0


gastroenterology

Neutrophil to lymphocyte ratio for predicting postoperative recurrence in Crohn’s disease patients with isolated anastomotic lesions

Rirong Chen et 10 al.

Mar 31, 2023 in Therapeutic Advances in Gastroenterology
Therapeutic Advances in Gastroenterology, Volume 16, Issue , January December 2023. Background : Patients with isolated anastomotic lesions (iAL) are common in postoperative Crohn’s disease (CD) and have heterogeneous prognosis. Objective : To investigate the prognostic value of neutrophil to lymphocyte ratio (NLR) in CD patients with iAL. Design : A bicenter retrospective cohort study. Method ...

immunology

Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

Danping Zheng, Eran Elinav et 29 al.

Mar 20, 2023 in Nature Immunology


science

Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.

Ce Tang et 19 al.

Mar 17, 2023 in Nature communications
Dectin-1 (gene Clec7a), a receptor for β-glucans, plays important roles in the host defense against fungi and immune homeostasis of the intestine. Although this molecule is also suggested to be involved in the regulation of tumorigenesis, the role in intestinal tumor development remains to be elucidated. In this study, we find that azoxymethane-dextran-sodium-sulfate-induced and ApcMin-induced int...


hepatology

Cellular and Molecular Mechanisms of Intestinal Fibrosis.

Xiaomin Wu, Ren Mao et 9 al.

Mar 10, 2023 in Gut and liver
Intestinal fibrosis associated stricture is a common complication of inflammatory bowel disease usually requiring endoscopic or surgical intervention. Effective anti-fibrotic agents aiming to control or reverse intestinal fibrosis are still unavailable. Thus, clarifying the mechanism underpinning intestinal fibrosis is imperative. Fibrosis is characterized by an excessive accumulation of extracell...

hepatology

Asian Organization for Crohn's and Colitis and Asian Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 1: Risk assessment.

Dong Ii Park, Suk-Kyun Yang et 22 al.

Jan 1, 2018 in Journal of gastroenterology and hepatology
Because anti-tumor necrosis factor (anti-TNF) therapy has become increasingly popular in many Asian countries, the risk of developing active tuberculosis (TB) among anti-TNF users may raise serious health problems in this region. Thus, the Asian Organization for Crohn's and Colitis and the Asian Pacific Association of Gastroenterology have developed a set of consensus statements about risk assessm...

gastroenterology

Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 2: management.

Dong Il Park, Suk-Kyun Yang et 22 al.

Jan 18, 2018 in Intestinal research
Because anti-tumor necrosis factor (anti-TNF) therapy has become increasingly popular in many Asian countries, the risk of developing active tuberculosis (TB) among anti-TNF users may raise serious health problems in this region. Thus, the Asian Organization for Crohn's and Colitis and the Asia Pacific Association of Gastroenterology have developed a set of consensus statements about risk assessme...

gastroenterology

Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology consensus on tuberculosis infection in patients with inflammatory bowel disease receiving anti-tumor necrosis factor treatment. Part 1: risk assessment.

Dong Il Park, Suk-Kyun Yang et 22 al.

Jan 18, 2018 in Intestinal research
Because anti-tumor necrosis factor (anti-TNF) therapy has become increasingly popular in many Asian countries, the risk of developing active tuberculosis (TB) among anti-TNF users may raise serious health problems in this region. Thus, the Asian Organization for Crohn's and Colitis and the Asia Pacific Association of Gastroenterology have developed a set of consensus statements about risk assessme...