Jan 1, 2011
in Chinese journal of radiological medicine and protection
Objective To investigate the effect of elemene on the radiosensitivity of A549 cells and its possible molecular mechanism.
Method The effect of radiosensitivity was detected by colony forming assay. The protein expressions of DNA-PKcs,Bcl-2 and P53 were detected with Western blot. The correlation between the protein expression of DNA-PKcs and Bcl-2,DNA-PKcs and P53 was analyzed.
Result Elemen...
The human genome encodes two melatonin receptors (MT1 and MT2) that relay melatonin signals to cellular interior. Accumulating evidence has linked melatonin to multiple health benefits, among which its anticancer effects have become well-established. However, the implications of its receptors in lung adenocarcinoma have so far remained incompletely understood. This study aims to investigate the re...
Nov 9, 2022
in Asia-Pacific Journal of Clinical Oncology
Objective To investigate the combined predictive value of the preoperative serum cancer antigen 125 (CA125) level and age at diagnosis among patients with early stage endometrial cancer (EC) after initial treatment.
Method We retrospectively analyzed data from patients with early stage EC from 1999 to 2015 in multiple institutions in China. All 447 patients received postoperative adjuvant rad...
Cancers, Vol. 14, Pages 5129: Utilization Trend and Comparison of Different Radiotherapy Modes for Patients with Early Stage High Intermediate Risk Endometrial Cancer: A Real World, Multi Institutional Study Cancers doi: 10.3390/cancers14205129 Authors: Kang Ren Lijuan Zou Tiejun Wang Zi Liu Jianli He Xiaoge Sun Wei Zhong Fengju Zhao Xiaomei Li Sha Li Hong Zhu Zhanshu Ma Shuai Sun Wenhui Wang Ke H...
Introduction Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rapidly progressive and easily metastatic high grade lung cancer, with a poor prognosis when distant metastasis (DM) occurs. The aim of our study was to explore risk factors associated with DM in LCNEC patients and to perform survival analysis and to develop a novel nomogram based predictive model for screening risk population...
Aug 28, 2022
in Nutrition, metabolism, and cardiovascular diseases : NMCD
Low-grade chronic inflammation was reported to serve as a distinctive pathophysiologic feature of coronary artery disease (CAD), the leading cause of death around the world. Herein, the current study aimed to explore whether and how microRNA-34c-5p (miR-34c-5p), a miRNA enriched in extracellular vesicles (EVs) originated from the activated platelet (PLT-EVs), affects the inflammation of human coro...
As a valuable ornamental plant, Sinningia hybrida Isas Murmur (S. hybrida) has genetic flower diversity, which has great potential to develop different flower characters in the horticultural market. The present study focuses on establishing a practical approach for the sustainable propagation of S. hybrida. Compared with aseptic seeding leaves explants, field grown leaves explants are more suitabl...
The dorso-lateral prefrontal cortex (DLPFC) and the anterior cingulate cortex (ACC) are two main regions that support bilingual language control during language production. Previous studies have suggested that the regions work together in language control processes. However, how they cooperate with each other during bilingual language production is far from clear. We addressed this issue by recrui...
Soil salinization is causing ecosystem degradation and crop yield reduction worldwide, and elucidation of the mechanism of salt-tolerant plants to improve crop yield is highly significant. Podocarpus macrophyllus is an ancient gymnosperm species with a unique environmental adaptation strategy that may be attributed to its lengthy evolutionary process. The present study investigated the physiologic...
This research aimed to provide an overview of the impact of adjuvant vaginal brachytherapy (VBT) and external beam pelvic radiotherapy (EBRT) with or without VBT on survival in stage I to II EC patients in China from a long-term multi-institutional analysis. We retrospectively analyzed stage I to II EC patients from 13 institutions treated between 2003 and 2015. All patients underwent surgical sta...