Federica Giardina

Publications : 42
Aldex : 80
H-index : 11
Citations : 337


medicine

Evaluating and mitigating the potential indirect effect of COVID-19 on control programmes for seven neglected tropical diseases: a modelling study.

Anna Borlase, Emma L Davis et 6 al.

Nov 1, 2022 in The Lancet. Global health
In line with movement restrictions and physical distancing essential for the control of the COVID-19 pandemic, WHO recommended postponement of all neglected tropical disease (NTD) control activities that involve community-based surveys, active case finding, and mass drug administration in April, 2020. Following revised guidance later in 2020, and after interruptions to NTD programmes of varying le...

infectiology

Appropriateness of the current parasitological control target for hookworm morbidity: A statistical analysis of individual-level data.

Veronica Malizia, Luc E Coffeng et 3 al.

Jun 28, 2022 in PLoS neglected tropical diseases
Soil-transmitted helminths affect almost 2 billion people globally. Hookworm species contribute to most of the related morbidity. Hookworms mainly cause anaemia, due to blood loss at the site of the attachment of the adult worms to the human intestinal mucosa. The World Health Organization (WHO) aims to eliminate hookworm morbidity by 2030 through achieving a prevalence of moderate and heavy inten...

Deworming women of reproductive age during adolescence and pregnancy: what is the impact on morbidity from soil-transmitted helminths infection?

Carolin Vegvari et 10 al.

Apr 23, 2021 in Parasites & vectors
Soil-transmitted helminths (STHs) are a major cause of poor health in low- and middle-income countries. In particular, hookworm is known to cause anaemia in children and women of reproductive age (WRA). One goal of the World Health Organization's (WHO) 2030 roadmap for neglected tropical diseases is to reduce STH-related morbidity in WRA. As a minimal intervention, the WHO recommends deworming ado...

neurology

Multiple N of 1 trials to investigate hypoxia therapy in Parkinson’s disease: study rationale and protocol

Jules M. Janssen Daalen et 8 al.

Jul 14, 2022 in BMC Neurology
Parkinson’s disease (PD) is a neurodegenerative disease, for which no disease modifying therapies exist. Preclinical and clinical evidence suggest that hypoxia based therapy might have short and long term ben...

pediatrics

An Italian Multicenter Study on the Epidemiology of Respiratory Syncytial Virus During SARS CoV 2 Pandemic in Hospitalized Children

Raffaella Nenna, Gaia Vanzù et 35 al.

Jul 14, 2022 in Frontiers in Pediatrics
Since the beginning of 2020, a remarkably low incidence of respiratory virus hospitalizations has been reported worldwide. We prospectively evaluated 587 children, aged <12 years, admitted for respiratory tract infections from 1 September 2021 to 15 March 2022 in four Italian pediatric hospitals to assess the burden of respiratory viruses during the COVID 19 pandemic in Italy. At admission, a Clin...

infectiology

Characteristics and outcome of vaccinated and non-vaccinated patients hospitalized in a single Italian HUB for COVID-19 during the Delta and Omicron waves in Northern Italy.

Francesca Rovida et 21 al.

Jun 21, 2022 in International journal of infectious diseases
We compared the characteristics and outcome of vaccinated and non-vaccinated patients hospitalized for COVID-19. Patients hospitalized in a COVID hub during three one-month periods were analysed: i) October 15th-November 15th, 2020 (pre-vaccination peak); ii) October 15th-Novembre 15th, 2021 (Delta wave); iii) December 15th, 2021-January 15th, 2022 (Omicron wave). To define the epidemiologic conte...

Vaccines, Vol. 10, Pages 703: Evaluation of the Neutralizing Antibodies Response against 14 SARS CoV 2 Variants in BNT162b2 Vaccinated Na&iuml ve and COVID 19 Positive Healthcare Workers from a Northern Italian Hospital

Josè Camilla Sammartino et 11 al.

Apr 29, 2022 in Vaccines
SARS CoV 2 still represents a global health burden, causing more than six million deaths worldwide. Moreover, the emergence of new variants has posed new issues in terms of vaccine efficacy and immunogenicity. In this study, we aimed to evaluate the neutralizing antibody response against SARS CoV 2 variants in different cohorts of vaccinated and unvaccinated subjects. Four fold diluted sera from S...

virology

Comparative analysis of SARS-CoV-2 quasispecies in the upper and lower respiratory tract shows an ongoing evolution in the spike cleavage site.

Stefano Gaiarsa et 13 al.

Apr 14, 2022 in Virus research
Studies are needed to better understand the genomic evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study aimed to describe viral quasispecies population of upper and lower respiratory tract by next-generation sequencing in patients admitted to intensive care unit. A deep sequencing of the S gene of SARS-CoV-2 from 109 clinical specimens, sampled from the upper ...

TropicalMed, Vol. 7, Pages 13: TB Hackathon: Development and Comparison of Five Models to Predict Subnational Tuberculosis Prevalence in Pakistan

Sandra Alba et 19 al.

Jan 17, 2022 in Tropical Medicine and Infectious Disease
Pakistans national tuberculosis control programme (NTP) is among the many programmes worldwide that value the importance of subnational tuberculosis (TB) burden estimates to support disease control efforts, but do not have reliable estimates. A hackathon was thus organised to solicit the development and comparison of several models for small area estimation of TB. The TB hackathon was launched in ...

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Enrico Gratton