Alviss

Lack of stability guarantees strongly limits the use of reinforcement learning (RL) in safety critical robotic applications. Here we propose a control system architecture for continuous RL control and derive corresponding stability theorems via contraction analysis, yielding constraints on the network weights to ensure stability. The control architecture can be implemented in general RL algorithms...

The objective of this study was to assess the clinical significance of determining the levels of matrix metalloproteinase-2 (MMP-2), MMP-9, tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), and TIMP-2 in the peripheral blood of patients with differentiated thyroid carcinoma (DTC). Forty-nine patients with benign thyroid lesions and 57 patients with DTC were examined using the enzyme-linked ...

This study aimed to analyze the clinical characteristics and potential predictors of disease severity in patients with coronavirus disease 2019 (COVID-19). We retrospectively analyzed the clinical data from 64 (37 male and 27 female) patients with COVID-19. Their mean age was 47.8 years; 43 (67.2%) cases were non-severe, 21 (32.8%) were severe, and 2 patients (3.1%) died. Age and serum ferritin le...

ACS OmegaDOI: 10.1021/acsomega.2c05376

Chronic inflammation and T cell dysregulation persist in individuals infected with human immunodeficiency virus type 1 (HIV-1), even after successful antiretroviral treatment. The mechanism involved is not fully understood. Here, we used Olink proteomics to comprehensively analyze the aberrant inflammation-related proteins (IRPs) in chronic HIV-1-infected individuals, including in 24 treatment-naï...

The increasing complexity of industrial processes brings new challenges to fault diagnosis tasks, and different types of faults have higher and higher requirements on the performance of fault classification models. This paper proposes a novel multivariate nonlinear temporal related fault diagnosis method based on gated recurrent units. First, to improve the performance of the model in local infor...

Eleven novel NNN Cu(II) complexes supported by a tridentate bis(imidazo[1,2-α]pyridin-2-yl)pyridine ligand were synthesized and characterized by elemental analysis, HRMS, and X-ray determination. Target prediction and docking studies indicated that these pincer complexes formed hydrogen bonds with Asp33 and Gly35 of Cathepsin D protein, which is highly associated with prognosis of advanced prostat...