Alexandra D. Voloshina

Publications : 68
Aldex : 30
H-index : 12
Citations : 415

pharmacology

Pharmaceutics, Vol. 14, Pages 1508: Molecular and Nano Structural Optimization of Nanoparticulate Mn2 plus Hexarhenium Cluster Complexes for Optimal Balance of High T1 and T2 Weighted Contrast Ability with Low Hemoagglutination and Cytotoxicity

Bulat Salavatovich Akhmadeev et 11 al.

Jul 20, 2022 in Pharmaceutics
Pharmaceutics, Vol. 14, Pages 1508: Molecular and Nano Structural Optimization of Nanoparticulate Mn2+ Hexarhenium Cluster Complexes for Optimal Balance of High T1 and T2 Weighted Contrast Ability with Low Hemoagglutination and Cytotoxicity Pharmaceutics doi: 10.3390/pharmaceutics14071508 Authors: Bulat Salavatovich Akhmadeev Irek R. Nizameev Kirill V. Kholin Alexandra D. Voloshina Tatyana P. Gera...

Nanomaterials, Vol. 12, Pages 1986: Supramolecular Self Assembly of Porphyrin and Metallosurfactant as a Drug Nanocontainer Design

Ruslan R. Kashapov et 9 al.

Jun 9, 2022 in Nanomaterials
Nanomaterials, Vol. 12, Pages 1986: Supramolecular Self Assembly of Porphyrin and Metallosurfactant as a Drug Nanocontainer Design Nanomaterials doi: 10.3390/nano12121986 Authors: Ruslan R. Kashapov Yuliya S. Razuvayeva Svetlana S. Lukashenko Syumbelya K. Amerhanova Anna P. Lyubina Alexandra D. Voloshina Victor V. Syakaev Vadim V. Salnikov Lucia Y. Zakharova The combined method of treating malig...

chemistry

Cationic Imidazolium Amphiphiles Bearing a Methoxyphenyl Fragment: Synthesis, Self Assembly Behavior, and Antimicrobial Activity

Darya A. Kuznetsova et 10 al.

Apr 11, 2022 in Langmuir
LangmuirDOI: 10.1021/acs.langmuir.2c00299

chemistry

Synthesis and biological evaluation of taurine‐derived diarylmethane and dibenzoxanthene derivatives as possible cytotoxic and antimicrobial agents

Andrey V. Smolobochkin et 9 al.

Mar 9, 2022 in Chemistry & Biodiversity
The series of novel taurine‐derived diarylmethanes and dibenzoxanthenes was synthesized starting from simple commercially available precursors via modular three‐stage approach. All the newly synthesized compounds were screened for in vitro antibacterial and antifungal activity, as well as cytotoxicity towards normal and cancer cell lines. Some of the synthesized compounds exhibited 2‐4‐fold higher...

IJMS, Vol. 22, Pages 13148: Antimicrobial Properties and Cytotoxic Effect of Imidazolium Geminis with Tunable Hydrophobicity

Syumbelya K. Amerkhanova et 8 al.

Dec 5, 2021 in International Journal of Molecular Sciences
Antimicrobial, membranotropic and cytotoxic properties of dicationic imidazolium surfactants of n s n (Im) series with variable length of alkyl group (n = 8, 10, 12, 14, 16) and spacer fragment (s = 2, 3, 4) were explored and compared with monocationic analogues. Their activity against a representative range of Gram positive and Gram negative bacteria, and also fungi, is characterized. The relatio...

chemistry

A novel salt-responsive hydrogel on the base of calixresorcinarene–mPEG amide conjugate

Alina M. Shumatbaeva et 9 al.

Jan 1, 2020 in Colloids and Surfaces A
A novel low toxic amide calix[4]resorcinarene–mPEG conjugates of amphiphilic and dendrimeric character were synthesized. It was shown that the growth of the temperature or the ionic strength growth of the solution leads to different demonstration of the amplification of hydrophobic interactions in the conjugates self-associates. It was found that in PBS or 0.9 % NaCl solutions the amphiphilic con...

chemistry

Triphenylphosphonium conjugates of 1,2,3-triazolyl nucleoside analogues. Synthesis and cytotoxicity evaluation

Irina Yu. Strobykina et 11 al.

Jan 1, 2020 in Medicinal Chemistry Research
A series of triphenylphosphonium (TPP) conjugates of 1,2,3-triazolyl analogues of several pyrimidine nucleosides was synthesized and evaluated for the in vitro cytotoxicity against human cancer cell lines M-HeLa, MCF-7, PANC-1, PC-3, DU145, SKOV-3, A275, and normal human cell line WI-38. In these TPP-conjugates triphenylphosphonium cation was attached via a tetramethylene chain to the N-3 atom of ...



chemistry

Doxorubicin delivery by polymer nanocarrier based on N-methylglucamine resorcinarene

Tatiana Yu. Sergeeva et 9 al.

Jan 1, 2020 in Supramolecular Chemistry
ABSTRACT Herein we describe a simple method for the synthesis of polymer nanocarrier for the doxorubicin delivery. The nanocarrier consists of N-methyl-glucamine resorcinarenes that are covalently bound to phenylboronic acid. The nanocarrier is stable at normal pH but is hydrolysed at pH below 6. It demonstrates low cytotoxicity and haemolytic activity. Doxorubicin was successfully loaded into the...

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